CSE expression, and H 2 S content were significantly reduced in granulation tissues of wounds in ob/ob mice compared with control mice. Inflammation and angiogenesis in granulation tissues of the wounds were examined. Effects of NaHS on wound healing were evaluated. Full-thickness skin dorsal wounds were created on ob/ob mice and C57BL/6 mice.Ĭystathionine-γ-lyase (CSE) expression and H 2 S production were determined in granulation tissues of the wounds. We aim to investigate the role of H 2 S in impaired wound healing in ob/ob mice and explore the possible mechanisms involved. Hydrogen sulfide (H 2 S) has been reported to have multiple biological activities. Zhao, Huichen Lu, Shengxia Chai, Jiachao Zhang, Yuchao Ma, Xiaoli Chen, Jicui Guan, Qingbo Wan, Meiyan Liu, YuantaoThe proposed mechanisms of impaired wound healing in diabetes involve sustained inflammation, excess oxidative stress and compromised agiogenesis. Using A Computer Software For Solving Lp The Optimal Solution Achieved Is.Contoh Soal Riset Operasional Metode Big M 2.
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